Association between different insulin resistance surrogates and severe abdominal aortic calcification: A cross‑sectional study.

ABSTRACT: Abdominal aortic calcification (AAC) is a well-established predictor of cardiovascular morbidity and mortality. Although insulin resistance (IR) is implicated in vascular calcification, evidence on the association between IR surrogates and severe AAC remains limited. A cross-sectional analysis of 1230 participants was conducted using data from the 2013 to 2014 National Health and Nutrition Examination Survey (NHANES). Multiple regression and generalized additive models (GAM) were employed to evaluate the associations between IR surrogates (TyG index, homeostasis model assessment of insulin resistance (HOMA-IR), and METS-IR) and severe AAC. The predictive performance of the triglyceride glucose (TyG) index and its derived indicators in predicting severe AAC was assessed using receiver opera

SUBMITTER: Wang T 

PROVIDER: S-EPMC12459475 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature