Systematic review and meta-analysis of cardiovascular event incidence and risk factors in pediatric dialysis patients.

ABSTRACT:

Background

Cardiovascular disease (CVD) and left ventricular hypertrophy (LVH) are prevalent complications in pediatric and adolescent dialysis patients, elevating morbidity and mortality risks. Despite existing studies on cardiovascular risks, a systematic synthesis of their prevalence and contributing factors is lacking. This study aims to establish an evidence-based foundation to guide clinical interventions.

Methods

We systematically searched PubMed, Embase, Cochrane Library, and Web of Science until March 2025. Cardiovascular events and determinants were descriptively analyzed, while LVH prevalence underwent meta-analysis using a random-effects model. Heterogeneity sources were explored via sensitivity and subgroup analyses (stratified by dialysis modality and study qua

SUBMITTER: Zheng X 

PROVIDER: S-EPMC12459514 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature