The neutrophil-to-lymphocyte ratio in rheumatoid arthritis: The dual perspectives from literature and clinic.

ABSTRACT: The aim of this study was to elucidate the research direction and application value of neutrophil-to-lymphocyte ratio (NLR) as an emerging inflammatory marker in rheumatoid arthritis (RA) from both literature and clinical perspectives. Firstly, we made an extensive analysis in terms of the number of publications, highly cited literature, co-cited references, and keywords. Subsequently, a retrospective exploration of clinical data of 1490 patients with rheumatic diseases admitted to the First Affiliated Hospital of Anhui University of Chinese Medicine was conducted. Logistic regression models were used to explore the independent predictive role of NLR in different scenarios. Nomogram was developed and the model was clinically evaluated by recipient operating characteristic (ROC) curves, cal

SUBMITTER: Li Y 

PROVIDER: S-EPMC12459527 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature