Endocrine complications after solid organ transplantation in childhood and adolescents.

ABSTRACT:

Objective

Acute or chronic metabolic derangement following solid organ transplantation (SOT) often leads to endocrine complications, which have become more common as survival rates post-SOT have improved. This study was performed to investigate long-term endocrine complications after SOT in children and adolescents.

Methods

This study included 259 pediatric patients who underwent SOT, including kidney (n = 43), liver (n = 170), lung (n = 5), heart (n = 37), and multi-organ (n = 4), with a minimum follow-up period of 5 years post-transplant. Clinical and endocrinological data were retrospectively collected, including information on growth, obesity, diabetes, dyslipidemia, thyroid disease, bone health, and pubertal development.

Results

Of 259 patients, 203 (78.4%) devel

SUBMITTER: Yoon JH 

PROVIDER: S-EPMC12460080 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature