The risk prediction model for acute urine retention after perineal prostate biopsy based on the LASSO approach and Boruta feature selection.

ABSTRACT:

Objective

One known side effect of transperineal (TP) prostate biopsies is acute urine retention (AUR). We aimed to create and evaluate a predictive model for the post-paracentesis risk of acquiring AUR.

Methods

This study included 599 patients undergoing prostate biopsies (April 2020-July 2023) at the Second Affiliated Hospital of Nantong University, selected based on abnormal digital rectal examination and/or PSA (prostate-specificantigen) > 4 ng/mL. Acute urinary retention (AUR) was defined as the inability to void within 72 hours post-biopsy, requiring catheterization. Patients were randomly divided into training (419 cases) and test (180 cases) sets. Univariate logistic analysis and feature selection Boruta and LASSO (Least absolute shrinkage and selection operator) ide

SUBMITTER: Shen C 

PROVIDER: S-EPMC12460100 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature