Replay and representation dynamics in the hippocampus of freely flying bats.

ABSTRACT: Cognitive functions for navigation and memory rely on emergent properties of neural ensembles in the hippocampus, such as activity replay^1-5 and theta sequences^6-9. However, whether and how these phenomena generalize across species with distinct navigational demands and neurophysiological properties remains unclear. Here we wirelessly recorded neural activity from large populations of cells and local field potentials from the hippocampus of freely flying Egyptian fruit bats (Rousettus aegyptiacus) engaged in free, spontaneous foraging behaviour. During rest, we identified time-compressed forward and reverse replays of multiple flight trajectories coinciding with sharp-wave ripples. Notably, replays occurred predominantly at locations that were both spatially and tempo

SUBMITTER: Forli A 

PROVIDER: S-EPMC12460160 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature