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Drugs for Procedural Sedation and Analgesia in Children: A Systematic Review and Meta-analysis.


ABSTRACT:

Background and objectives

Performing medical procedures on children can often be challenging because of the anxiety that these procedures may induce, the need for immobility that they may require, or age-related development capabilities. We assessed the effects of procedural sedation and analgesia drugs for anxiety management in children during medical procedures.

Methods

We searched PubMed Medline, Cochrane Library, American Academy of Pediatrics, Cumulative Index to Nursing and Allied Health Literature, ClinicalTrials.gov, and references of eligible studies. We included parallel-arm randomized controlled trials comparing different active drugs of procedural sedation and analgesia in children undergoing diagnostic or therapeutic, painful or nonpainful procedures. Two author

SUBMITTER: Hamdan S 

PROVIDER: S-EPMC12460213 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature