Epidemiology, drug resistance, and clinical risk factors of peritoneal dialysis-associated peritonitis: a five-year multicenter study.

ABSTRACT:

Background

Peritoneal dialysis-associated peritonitis (PDAP) remains a major complication in long-term dialysis patients, leading to significant morbidity and healthcare burden. This study aimed to investigate the microbial spectrum, antimicrobial resistance patterns, and clinical risk factors associated with PDAP in hospitalized patients in Anhui, China, over the past five years.

Methods

A retrospective analysis was conducted on 438 peritoneal dialysis (PD) patients from three PD centers in Anhui from 2020 to early 2025. Of these, 238 patients were diagnosed with PDAP and 200 served as controls without peritonitis. Peritoneal effluents were cultured and microbiologically identified using MALDI-TOF MS and VITEK 2 systems. Antimicrobial susceptibility testing followed CLSI M1

SUBMITTER: Zhang M 

PROVIDER: S-EPMC12460227 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature