Association between hospital volume and outcomes in ovarian cancer: a systematic review.

ABSTRACT:

Background

Hospital surgical volume has been proposed as a determinant of ovarian cancer (OC) outcomes, but findings remain inconsistent.

Objective

To systematically assess the association between hospital volume and outcomes in OC patients.

Methods

A systematic search of PubMed, Embase, and Cochrane Library was conducted through January 2025. Fifteen observational studies involving over 100,000 OC patients were included and qualitatively synthesized.

Results

Thirteen of fifteen studies demonstrated that treatment in high-volume hospitals was significantly associated with improved overall survival (OS). Reported benefits included a 5-year OS increase from 22.3% to 55.0%, and up to 3% OS gain per 20 additional surgeries per year. High-volume centers also showed

SUBMITTER: Luo Q 

PROVIDER: S-EPMC12460345 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature