Prognostic impact of collateral circulation in direct thrombectomy versus bridging thrombectomy for acute ischemic stroke patients with anterior circulation large vessel occlusion: a retrospective comparative study.

ABSTRACT:

Objective

To evaluate the prognostic impact of collateral circulation on outcomes of direct thrombectomy (DT) versus bridging thrombectomy (BT) for acute ischemic stroke (AIS) patients with anterior circulation large vessel occlusion (LVO).

Method

This retrospective study included 460 AIS patients with anterior circulation LVO who underwent either DT (n = 220) or BT (n = 240). Collateral status was assessed using multiphase computed tomographic angiography. The primary outcome was functional prognosis at 3 months, measured by the modified Rankin Scale (mRS). Prognostic factors for good prognosis (90-day mRS ≤ 2) and adverse events were identified through multivariate logistic regression and receiver operating characteristic (ROC) analyses.

Results

The BT

SUBMITTER: Li Z 

PROVIDER: S-EPMC12460346 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature