External validation of a prediction model for bleeding events in anticoagulated cancer patients with venous thromboembolism (PredictAI).

ABSTRACT:

Objective

The objective of this study was to validate the PredictAI models for predicting major bleeding (MB) in patients with active cancer and venous thromboembolism (VTE) with anticoagulant (ACO) therapy, within 6 months after primary VTE, using an independent cohort of patients from the TESEO database.

Methods

This study conducted an external validation of the PredictAI models using the international, prospective TESEO registry from July 2018 until October 2021. Data from 40 Spanish and Portuguese hospitals recruiting consecutive cases of cancer-associated thrombosis under anticoagulant treatment and without missing values regarding the model outcome or predictors were used. Patients with baseline MB or unknown MB status during follow-up were excluded for the validation

SUBMITTER: Vinuela-Beneitez MC 

PROVIDER: S-EPMC12460363 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature