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Milrinone versus dobutamine in acute myocardial infarction-related cardiogenic shock; a propensity score matched analysis.


ABSTRACT:

Background

Vasopressors and inotropes remain the cornerstone in treatment of acute myocardial infarction-related cardiogenic shock (AMI-CS). Milrinone and dobutamine are both commonly used, yet the optimal inotrope remains unclear. We aimed to identify factors associated with milrinone and dobutamine treatment and assess their effects on 30-day mortality in a large real-world cohort of AMI-CS patients. The Netherlands Heart Registration prospectively records data for percutaneous coronary intervention patients. Between 2017 and 2021, additional retrospective data on CS patients were collected by fourteen Dutch hospitals. Patients who were treated with either milrinone or dobutamine were selected; those treated with both were excluded. Missing data were imputed (30 ×) using multiple

SUBMITTER: Ten Berg S 

PROVIDER: S-EPMC12460367 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature