Emergence and characterization of mixed Candida auris strain infections in China.

ABSTRACT:

Purpose

The multidrug-resistant fungal pathogen Candida auris poses an increasing global health threat due to its high transmissibility and persistence in healthcare environments. We aimed to explore the potential cases of mixed C. auris-strain colonizations or infections in China and to investigate the genetic and biological diversity of the associated isolates.

Methods

C. auris isolates from 5 colonization or infection cases were distinguished by colony morphology and verified by D1/D2-ITS alignment. Phylogenetic and genomic diversity analysis of all isolates were conducted using whole genome sequences. Comparative biological analysis of all isolates, including cellular and colony morphology, antifungal susceptibility, biofilm formation, SAP activity, and both in vitro and

SUBMITTER: Du H 

PROVIDER: S-EPMC12460497 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature