Process development for antifungal production by Bacillus subtilis BS20: nanoparticle supplementation, process optimization and preliminary scale-up studies.

ABSTRACT: The intensive agricultural practices used to meet global crop production demands have resulted in rigorous use of chemical pesticides. These ultimately compromise crop production as well as the environment. To alleviate these challenges, cheaper and environmentally friendly biocontrol agents have been considered as an alternative to chemical pesticides. Hence, this study was undertaken with the aim of enhancing antifungal production by Bacillus subtilis BS20 through process modeling, optimization, nanocatalysis and subsequent assessment of the scale up potential of the optimized process. The investigated process parameters included glucose concentration (10-30 g/L), incubation temperature (25-45 ℃) and incubation time (24-96 h). Optimized process conditions of 11.5 g/L glucose concentratio

SUBMITTER: Nzimande SN 

PROVIDER: S-EPMC12460514 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature