Ultrasound clusters of joint inflammation in systemic lupus erythematosus: a cross-sectional study.

ABSTRACT: Despite the high frequency of Systemic Lupus Erythematosus (SLE)-related joint involvement, few studies investigated the anatomical distribution of this manifestation. In the present study, by applying musculo-skeletal ultrasound (US), we aimed at mapping joint involvement in a large cohort of SLE patients. We enrolled SLE patients with past or present joint involvement. US evaluation was performed at level of metacarpophalangeal joints (MCPs), proximal interphalangeal (PIPs) joints, wrists, knees, and metatarsophalangeal (MTPs) joints. Grey scale synovitis and Power Doppler were scored according to the EULAR-OMERACT ultrasound scoring system (range 0-3). Principal Component Analysis (PCA) and Unsupervised Hierarchical Cluster Analysis (CA) were performed to define the presence of clusters

SUBMITTER: Natalucci F 

PROVIDER: S-EPMC12460540 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature