Epidemiology and outcomes of Candida spp. bloodstream infections in cancer patients: a comparative retrospective study from a German tertiary cancer center.

ABSTRACT:

Background

Bloodstream infections (BSI) due to Candida spp. significantly contribute to morbidity and mortality among cancer patients. Understanding their clinical course, risk factors, and outcomes compared to bacterial BSI is essential.

Aim

We aim to elucidate the epidemiology and risk factors associated with Candida BSI compared to bacterial BSI in cancer patients.

Methods

We analyzed epidemiological data of Candida BSI versus bacterial BSI among cancer patients, primarily with hematological malignancies. Blood cultures were obtained upon clinical suspicion, with species identification by VITEK 2 and MALDI-TOF. Susceptibility testing utilized VITEK 2 or antibiotic gradient tests.

Results

Candida BSI was associated with higher 30-day mortality compared to bac

SUBMITTER: Wolf S 

PROVIDER: S-EPMC12460568 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature