Topical ophthalmic anesthetics for corneal abrasions: findings from a Cochrane systematic review and meta-analysis.

ABSTRACT:

Background

Despite potential benefit, outpatient use of topical ophthalmic anesthetics can result in poor healing, infection, scar, and blindness. An unbiased analysis of randomized controlled trials (RCTs) is needed to examine their effectiveness and safety compared with placebo or other treatments for corneal abrasions.

Methods

Cochrane Central Register of Controlled Trials, MEDLINE, Embase.com, Latin American and Caribbean Health Sciences, ClinicalTrials.gov, and the World Health Organization International Clinical Trials Registry Platform were searched on February 10, 2023, without restriction on language or publication date. The published review protocol served as registration.

Results

Systematic review and meta-analysis of nine RCTs describing 314 participants w

SUBMITTER: Leslie L 

PROVIDER: S-EPMC12460648 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature