A Prospective Study on Potentially Inappropriate Drug Use and All-Cause Mortality in Community-Dwelling Older Adults.

ABSTRACT:

Background

Potentially inappropriate prescribing (PIP), encompassing potentially inappropriate medications (PIMs) and prescribing omissions (PPOs), is prevalent among older adults and consistently associated with adverse health outcomes. However, evidence on its impact on mortality remains limited. We examined the associations of PIMs and PPOs with long-term mortality in a cohort of community-dwelling older adults.

Methods

One thousand two hundred and ten participants from the third follow-up (1999-2007) of a longitudinal prospective cohort study were followed for mortality until 03/2022. PIMs and PPOs were identified using the 2023 Beers and the Screening Tool of Older Persons' Potentially Inappropriate Prescriptions/Screening Tool to Alert doctors to Right Treatment (STOPP

SUBMITTER: Orenstein L 

PROVIDER: S-EPMC12460961 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature