Longitudinal Association of Inflammatory Diets on Cognition in Older Adults: Insights from the Oral-Gut-Brain Axis.

ABSTRACT:

Background

The oral-gut-brain axis is known to influence dementia development, but the interactions between an inflammatory diet, inflammatory conditions such as periodontitis and Helicobacter pylori (Hp) infection, and their effects on cognitive function remain unclear. This study aims to investigate how periodontitis and Hp infection affect the association between an inflammatory diet and cognitive performance.

Methods

This prospective cohort study was conducted from 2011 to 2019, involving community-dwelling older adults (≥ 65 years old) without dementia, recruited between 2011 and 2013 (N = 511). At baseline, dietary inflammatory potential was assessed by the Empirical Dietary Inflammatory Index (EDII) using a 44-item semi-quantitative food frequency questionnaire. Perio

SUBMITTER: Chou YC 

PROVIDER: S-EPMC12460988 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature