Altered Topology of Brain Structural Network in Patients With Migraine Without Aura: A Structural MRI Study.

ABSTRACT:

Background

Migraine is a neurovascular disease associated with significant morbidity and disability, but its underlying pathophysiology remains elusive. Functional alterations within the brain are frequently observed in individuals with migraine, whereas structural changes are less frequently documented. This study was primarily designed to investigate topological abnormalities in brain structural networks in patients with migraine using structural magnetic resonance imaging.

Methods

Graph theoretical analysis was used to compare global and regional topological properties of grey matter structural networks in 37 migraine patients and 44 age-, gender-, and education-matched healthy controls. Structural correlation networks were constructed for both groups on the basis of meas

SUBMITTER: Cao ZM 

PROVIDER: S-EPMC12461235 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature