Bilateral carcinoid heart disease secondary to a massive right-to-left shunt through a patent foramen ovale: a case report.

ABSTRACT:

Background

Carcinoid heart disease (CHD) is a rare complication of neuroendocrine tumours (NET). It typically involves the right-sided heart valves due to the effect of vasoactive substances. Bilateral involvement is uncommon and usually requires a significant right-to-left shunt through a patent foramen ovale (PFO).

Case summary

A 75-year-old woman with metastatic well-differentiated NET presented with progressive dyspnoea. Transthoracic echocardiography showed multivalvular involvement, including the tricuspid, mitral, and aortic valves, secondary to CHD. During preoperative assessment for valve replacement, the patient developed refractory hypoxaemia. A large right-to-left shunt through a high-risk PFO was confirmed by transoesophageal echocardiography. Percutaneous PFO c

SUBMITTER: Bertolin Boronat J 

PROVIDER: S-EPMC12461251 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature