3D-Printed Polysaccharide Scaffolds with NIR-Triggered Activity for Diabetic Wound Healing.

ABSTRACT: Skin restoration in patients with diabetes constitutes a significant therapeutic challenge as sustained hyperglycemia interferes with fundamental processes such as angiogenesis, cell regeneration, and inflammation control. These alterations not only delay healing but also increase the risk of infections and complications. Emerging therapeutic strategies such as photothermal irradiation have gained attention for their potential to accelerate tissue repair. In this study, we developed novel three-dimensional (3D)-printed near-infrared (NIR)-responsive scaffolds based on chondroitin sulfate, hyaluronic acid, alginate, and nanofibrillated cellulose, with and without polydopamine photothermal nanoparticles, as a new approach to addressing complex tissue regeneration. The resulting 3D multicompo

SUBMITTER: Salazar Salas BM 

PROVIDER: S-EPMC12461302 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature