Natural courses of atrial fibrillation following cryptogenic stroke: A systematic review and meta-analysis.

ABSTRACT:

Background

Cryptogenic stroke (CS) presents challenges in management and increases risk of stroke recurrence. The clinical relevance of atrial fibrillation detected after stroke (AFDAS) remains equivocal.

Methods

Our study was conducted in a meta-analysis design, including all observational studies and utilizing random-effects model. The objectives were to explore the association between predictors and AFDAS incidence, and clinical differences between AF and non-AF patients following CS.

Results

This meta-analysis included 59 studies with 18,683 patients with CS. AFDAS incidence was 20.8 %. In univariable analysis, significant predictors of AFDAS were age >75 years (OR 6.94, 95 % CI: 3.12-15.43, I² = 0 %) and hypertension (OR 2.16, 95 % CI: 1.28-3.63, I

SUBMITTER: Pajareya P 

PROVIDER: S-EPMC12461730 | biostudies-literature | 2025 Jul-Aug

REPOSITORIES: biostudies-literature