Ascending and Descending Pharyngeal Opening Pressures During Drug-Induced Sleep Endoscopy: Mechanistic Insights for Sleep Surgeons.

ABSTRACT:

Objective

To assess whether differences exist between ascending pharyngeal opening pressure (PhOP_A) and descending pharyngeal opening pressure (PhOP_D) obtained from positive airway pressure (PAP) titrations during drug-induced sleep endoscopy (DISE) and to identify the associations between the physiologic and anatomic constituents of these differences.

Study design

Cross-sectional study of a prospective, single-site sleep surgery cohort.

Setting

Quaternary care center.

Methods

Consecutive patients with obstructive sleep apnea undergoing DISE with PAP were enrolled. PAP was raised in a stepwise manner until inspiratory airflow limitation was abolished (PhOP_A), then decreased until just before airflow limitation reappeared (PhOP

SUBMITTER: Magana LC 

PROVIDER: S-EPMC12461826 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature