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Case Report: Idiopathic calvarial hyperostosis and concurrent nasal discharge in a 22-week-old Staffordshire bull terrier.


ABSTRACT: A 22-week-old Staffordshire bull terrier presented with acute onset of bilateral mucopurulent nasal discharge and lethargy. Clinical examination revealed pyrexia and pain upon palpation of the head, accompanied by marked asymmetrical swelling. Computed tomography (CT) of the head showed severe thickening of multiple calvarial bones with periosteal reaction, with small defined areas of fluid accumulation and contrast enhancement of the osteopenic areas. There was mild thickening of the mucosa of the frontal sinuses suggestive of sinusitis, fluid in the left nasal passage, choanae, and nasopharynx. Histological examination of biopsies of the bone revealed periosteal reaction with fibrosis, neutrophilic and histiocytic inflammation, and necrosis. Culture yielded negative results. The dog was

SUBMITTER: Travail V 

PROVIDER: S-EPMC12461860 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature