Temporal changes in prevalence and geographical distribution of human papillomavirus infection in mainland China: a systematic review and analysis of 1.07 million females from 2010 to 2021.

ABSTRACT:

Background

Human papillomavirus (HPV) has been identified as a causative agent of cervical cancer. The aim of this study was to investigate temporal changes in prevalence and geographical distribution of human papillomavirus (HPV) infection in mainland China.

Methods

This study was a systematic review and aggregate data analysis. The literature was searched from multiple databases. The included studies were divided into two groups, the 2010-2016 group and the 2017-2021 group, according to the time period of specimen collection. A total of 17 HPV types were selected. Temporal changes in prevalence and geographical distribution of HPV infection and the effect of the HPV vaccine were analyzed.

Results

A total of 1,073,296 females from mainland China were included. The to

SUBMITTER: Chen Q 

PROVIDER: S-EPMC12461961 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature