Evaluation of Long-Term Key Outcomes and Safety in Pulmonary Embolism: The EKOS-PE Study.

ABSTRACT:

Background

Pulmonary embolism (PE) is a major cause of morbidity and mortality, particularly in massive and submassive cases that lead to right ventricular (RV) strain and long-term complications. The EkoSonic Endovascular System (EKOS) offers a catheter-directed thrombolytic treatment option for patients with contraindications to systemic thrombolysis, but data on long-term outcomes remain limited. We aimed to evaluate long-term mortality, RV function, and quality of life (QoL) in patients with massive or submassive PE who were treated with EKOS therapy.

Methods

The EKOS-PE is a retrospective cohort study of 137 patients with massive or submassive PE who underwent EKOS therapy within a single health care system from 2020 to 2024. The primary outcome was all-cause mortality;

SUBMITTER: Sayfo S 

PROVIDER: S-EPMC12462068 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature