Identification and Successful Treatment of Intrahepatic Cholangiocarcinoma After Fontan Procedure.

ABSTRACT:

Background

Fontan-associated liver disease (FALD) increases the risk of malignant liver complications in patients with Fontan circulation.

Case summary

We present a case of intrahepatic cholangiocarcinoma in a patient with Fontan circulation, diagnosed using targeted biopsy for a hepatic lesion found during heart transplant evaluation. The patient underwent successful tumor resection with adjuvant chemotherapy and has been recurrence-free for 2 years.

Discussion

Although hepatocellular carcinoma (HCC) is more common in patients with FALD, this is the fifth published case of intrahepatic cholangiocarcinoma in a patient with Fontan circulation, with the longest reported follow-up after successful treatment. Targeted liver biopsy was integral in the diagnosis to provide

SUBMITTER: Minick MW 

PROVIDER: S-EPMC12462095 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature