Screening for individuals with postpartum depression by an attenuated and delayed niacin skin flushing response: a case control study.

ABSTRACT:

Background

Postpartum depression (PPD) affects maternal mental health extensively and is challenged by the lack of objective diagnostic methods. This study aimed to explore the characteristics of niacin skin flush response, a diagnostic marker for depression, in individuals with PPD and to determine its clinical potential as an adjunctive screening marker.

Methods

A total of 1417 parturients was recruited in this study. Edinburgh Postnatal Depression Scale was used to screen for depression with a cut-off score ≥ 13. The Patient Health Questionnaire-9 scale was used to test the consistency of scale screening. The Chi-square test was used to compare the screening results of the two scales, and the reliability and validity of the two scales were discussed. Mann Whitney U test w

SUBMITTER: Wang D 

PROVIDER: S-EPMC12462174 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature