Global sex disparities in lifetime risk of alopecia areata: a systematic analysis from the global burden of disease study, 1990 to 2021.

ABSTRACT:

Background

Alopecia areata (AA) represents a significant autoimmune disorder affecting hair follicles, with sex differences that have yet to reach scientific consensus. The regional and temporal, age-related, and socioeconomic dimensions of sex-based lifetime risk disparities remain inadequately characterized and require further investigation.

Methods

(1) We estimated AA lifetime risk using the adjusted for multiple primaries method. We evaluated regional and temporal features of sex disparities through Average Annual Percentage Change analysis, with future projections to 2050 via ARIMA modeling. (2) Age-stratified sex disparity features were analyzed. (3) We evaluated AA risk associations with Socio-Demographic Index (SDI) variations through Spearman correlation analysis an

SUBMITTER: Sun J 

PROVIDER: S-EPMC12462261 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature