Real-world risk factors for incomplete cytoreduction in peritoneal carcinomatosis patients scheduled for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

ABSTRACT:

Background

Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment option for selected patients with peritoneal carcinomatosis. This study investigates preoperative factors influencing incomplete CRS.

Methods

We retrospectively reviewed 188 patients scheduled for curative-intent CRS/HIPEC between April 2015 and May 2023. Preoperative peritoneal cancer index (PCI) scores were determined using computed tomography (CT) (n = 155) and/or magnetic resonance imaging (MRI) (n = 82).

Results

Complete CRS was achieved in 126 patients (67.0%) and incomplete CRS in 62 (32.9%). Colorectal cancer was the predominant primary tumor (complete CRS: 42.9%; incomplete CRS: 50.0%), followed by ovarian cancer (34.1% vs. 17.7%). Multivariate analysi

SUBMITTER: Chen CY 

PROVIDER: S-EPMC12462296 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature