ScLineageAtlas: a comprehensive single-cell genomics database for characterizing cellular clones in cancer.

ABSTRACT: Accurate identification of clonal relationships between cell populations is crucial for investigating cellular differentiation trajectories and gaining insights into the underlying mechanisms of cancer initiation and development. The Single Cell Lineage Atlas (ScLineageAtlas; https://www.scladb.geneis.org.cn) is a comprehensive single-cell genomics database that characterizes cellular clones across various cancer types. The database currently includes 24 processed single-cell RNA sequencing datasets spanning 13 different cancer types. ScLineageAtlas leverages advanced computational methods to identify cellular clones, providing researchers with a detailed understanding of clone relationships and evolutionary dynamics. Additionally, the database offers comprehensive metadata for each sample

SUBMITTER: Liu J 

PROVIDER: S-EPMC12462628 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature