Heterogeneity Analysis of Associations Involving the Large-Scale Online MindCrowd Survey Memory Test.

ABSTRACT:

Introduction

Alzheimer's disease and related disorders (ADRDs), as well as general age-related cognitive decline, are known to be multifactorial with heterogeneous etiologies. Identifying and accommodating heterogeneity in any one ADRD-related data set can be pursued using different analytical techniques, each with different assumptions or purposes. For example, whereas a great deal of research has explored clustering individuals or variables that exhibit greater similarity in some way, little research has explored evidence for heterogeneity in the relationships between relevant outcomes, such as performance on a memory test, and risk factors such as environmental exposures, behaviors, or genetic factors among individuals.

Methods

We explored evidence of heterogeneity in the

SUBMITTER: Bhadra N 

PROVIDER: S-EPMC12462766 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature