An Antagonism Between Ethylene Signaling and DNA Methylation Orchestrates the Progression of Leaf Senescence in Non-heading Chinese Cabbage.

ABSTRACT: Leaf senescence significantly impacts both the yield and quality of non-heading Chinese cabbage (NHCC). Despite its importance, the molecular mechanisms underlying the initiation and progression of leaf senescence in NHCC remain poorly understood. Here, transcriptome changes are first profiled, and found that ethylene (ET) and salicylic acid (SA) signaling pathways are activated during leaf senescence. Further mining of ET, SA, and DNA methylation pathway genes identified that EIN3A and CMT2 are induced and repressed, respectively, during leaf senescence. A whole-genome bisulfite sequencing (WGBS) analysis revealed a global reduction of DNA methylation during leaf senescence, with the most dramatic decline occurring in the 1 kb regions upstream of transcription start sites (TSS) and downst

SUBMITTER: Zhang D 

PROVIDER: S-EPMC12463009 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature