Detecting Pain Correlates With Recovery in Acute Brain Injury Patients With Disorders of Consciousness.

ABSTRACT:

Objectives

To evaluate pain as measured by the critical care pain observation tool (CPOT) and its potential as a biomarker for recovery in acute brain injury (ABI) patients with disorders of consciousness (DoC).

Design

Prospective observational single-center study.

Setting

Neuroscience ICU 2020-2024.

Patients

ABI patients with DoC.

Interventions

None.

Measurements and main results

Data included demographic, clinical characteristics, and CPOT scores. Glasgow Outcome Scale-Extended (GOSE) was obtained at 3, 6, and 12 months. Descriptive statistics, correlation coefficients, and logistic regression models were calculated to assess relationships between pain and GOSE. Of 110 patients, 62 (56%) had traumatic brain injury, 45 (41%) intracerebral hemorrh

SUBMITTER: Houshmand J 

PROVIDER: S-EPMC12463170 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature