10 years of real-world data: long-term efficacy and safety of HyalOne^® for hip osteoarthritis.

ABSTRACT:

Background

Hip osteoarthritis (OA) is a leading cause of disability in older adults, yet long-term, non-surgical treatment options remain limited. Viscosupplementation with intra-articular hyaluronic acid has shown promise, but evidence for its sustained efficacy in hip OA is scarce. This study evaluates the 10-year efficacy and safety of repeated ultrasound (US)-guided injections of HyalOne^®/Hyalubrix^® 60 in patients with symptomatic hip OA.

Methods

A retrospective, observational, open-label study was conducted on 681 patients with symptomatic hip OA treated with HyalOne^® between 2010 and 2013, with follow-up through 2023. Patients received one US-guided intra-articular injection every 6 months, with additional injections as needed. Pain and

SUBMITTER: Migliore A 

PROVIDER: S-EPMC12463173 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature