Evaluation of a newly developed rapid ELISA to detect anti-Ehrlichia canis antibodies in dogs.

ABSTRACT: Canine monocytic ehrlichiosis (CME) is a globally prevalent disease with zoonotic potential primarily caused by the obligate intracellular bacterium Ehrlichia canis, transmitted by the ticks Rhipicephalus spp. to vertebrate hosts. In dogs, CME affects immune system cells, leading to subclinical infection or acute and chronic disease forms that impact multiple organs and potentially result in death if diagnosis is delayed. Diagnosis of canine ehrlichiosis is complex, typically involving cytology, polymerase chain reaction), and serological assays such as the indirect immunofluorescence antibody test (IFAT), considered the gold standard, and enzyme-linked immunosorbent assay (ELISA). Herein, we introduce EhrlichiaCHECK Ab ELISA, a novel rapid indirect ELISA for detecting anti-E. canis antibo

SUBMITTER: Ferrero I 

PROVIDER: S-EPMC12463349 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature