Treatment of Inpatient Opioid Withdrawal with Short-Acting Full Agonist Opioids at a Safety-Net Hospital.

ABSTRACT:

Background

Fentanyl use leads to increased opioid tolerance in people with opioid use disorder, complicating management of opioid withdrawal syndrome. While accepted as gold standard, methadone and buprenorphine may be insufficient to treat acute opioid withdrawal. Short-acting full agonist opioids (SAFAO) may improve treatment in the acute care setting.

Aim

Characterize use of SAFAO to treat opioid withdrawal syndrome for inpatients.

Setting

Urban safety-net hospital.

Participants

Inpatients with opioid use disorder.

Program description

Addiction Consult Team offers SAFAO to manage opioid withdrawal syndrome.

Program evaluation

We performed retrospective chart review of hospitalizations (n = 124) for patients with opioid use disorder who received

SUBMITTER: Steiner G 

PROVIDER: S-EPMC12463741 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature