Risk factors for coronary artery calcification in Chinese patients undergoing maintenance hemodialysis: a meta-analysis.

ABSTRACT:

Background

Chronic kidney disease (CKD) progression to end-stage renal disease (ESRD) increases cardiovascular disease (CVD) risk, with coronary artery calcification (CAC) affecting 70% of Chinese maintenance hemodialysis (MHD) patients. Prolonged MHD treatment is linked to calcium-phosphorus imbalance and accelerated CAC progression. However, conflicting findings on CAC risk factors persist due to methodological heterogeneity in existing studies.

Objective

To systematically analyze the risk factors for coronary artery calcification in patients undergoing maintenance hemodialysis in China.

Methods

We conducted a computer-assisted search of ten databases, including PubMed, Web of Science, CBM, Wanfang, CNKI, and VIP, for observational studies (cohort, case-control, and

SUBMITTER: Li M 

PROVIDER: S-EPMC12464000 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature