Cognitive appraisal modulates Theta Burst Stimulation effects on stress-reactive rumination and affect.

ABSTRACT: The DLPFC plays a central role in cognitive appraisal and stress regulation, as this process-particularly secondary appraisal, where individuals assess their ability to cope with a situation-significantly influences stress responses on both psychological and physiological levels. We conducted a study where we applied different types of Theta Burst Stimulation (intermittent (i)TBS vs. continuous (c)TBS vs. sham (s)TBS) to the left DLPFC to increase or decrease the cortical excitability of the prefrontal neural network. We then examined how participants responded psychologically and physiologically to a potent psychosocial stressor, the Trier Social Stress Test (TSST), and aimed to investigate the influence of secondary cognitive appraisal on the effects of TBS on the stress response. Depend

SUBMITTER: Int-Veen I 

PROVIDER: S-EPMC12464076 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature