Impaired Brachial Artery Reactivity in Young Adults With Clinically Quiescent Juvenile Dermatomyositis.

ABSTRACT:

Objective

This study characterized brachial artery reactivity, an ultrasound indicator of endothelial function, in young adults who had clinically quiescent juvenile dermatomyositis (JDM) compared with matched controls.

Methods

Twenty young adults with previous documentation of JDM 14.2 ± 3.9 years (mean ± SD) after onset of their JDM symptoms, who were no longer taking medications were enrolled, with 20 healthy control participants matched for age, race, sex and body mass index. They obtained ultrasound brachial artery reactivity testing and nailfold end row capillary loop count.

Results

Participants were 21.8 ± 4.2 years old (70% female) and were aged 7.6 ± 3.7 years at JDM onset. The JDM Disease Activity Score (DAS) was 1.9 ± 2.5 and primarily based on active skin

SUBMITTER: Pachman LM 

PROVIDER: S-EPMC12464089 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature