Volume of parasagittal dura is associated with blood markers of systemic inflammation.

ABSTRACT:

Background

The parasagittal dura (PSD) has been hypothesized to act as a neuro-immunological hub, though evidence in favor of the hypothesis is limited. The present study explored whether there is any association between volume and function of PSD and blood markers that may be indicative of systemic inflammation.

Methods

The patient material included 76 subjects examined with intrathecal contrast-enhanced magnetic resonance imaging (MRI) where the contrast served as a cerebrospinal fluid (CSF) tracer. They were dichotomized into a control- (Ctrl) and a CSF-group. We investigated the correlations between blood markers indicative of systemic inflammation and the volume of PSD, enrichment of tracer in the PSD, and blood-measures of CSF clearance. The blood markers included C-re

SUBMITTER: Eide P 

PROVIDER: S-EPMC12464140 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature