Bioelectrical impedance analysis to assess body water status during fluid infusion in a rat model of extracorporeal membrane oxygenation.

ABSTRACT: Fluid monitoring is vital in patients receiving extracorporeal membrane oxygenation (ECMO), but research on the value of bioelectrical impedance analysis (BIA) for such patients is rare. This study aimed to assess the effectiveness of BIA in monitoring body water changes during fluid therapy with ECMO support. Using a rat model of venoarterial and venovenous ECMO (n = 13 each), fluid was administered before and after initiation, every 30 min during the 120-min ECMO support, and after ECMO termination. Tetrapolar electrodes for BIA were attached to rats' upper and lower trunks, with measurements performed every minute. Three rats died and were excluded. Among the 23 rats analyzed, all BIA parameters changed significantly across eight time points: resistance at infinite frequency (R_inf<

SUBMITTER: Lee S 

PROVIDER: S-EPMC12464257 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature