End-to-end CNN-based deep learning enhances breast lesion characterization using quantitative ultrasound (QUS) spectral parametric images.

ABSTRACT: QUS spectral parametric imaging offers a fast and accurate method for breast lesion characterization. This study explored using deep CNNs to classify breast lesions from QUS spectral parametric images, aiming to enhance radiomics and conventional machine learning. Predictive models were developed using transfer learning with pre-trained CNNs to distinguish malignant from benign lesions. The dataset included 276 participants: 184 malignant (median age, 51 years [IQR: 27-81 years]) and 92 benign cases (median age, 46 years [IQR: 18-75 years]). QUS spectral parametric imaging was applied to the US RF data and resulted in 1764 images of QUS spectral (MBF, SS, and SI), along with QUS scattering parameters (ASD and AAC). The data were randomly split into 60% training, 20% validation, and 20% tes

SUBMITTER: Osapoetra LO 

PROVIDER: S-EPMC12464328 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature