Mesoporous Potassium-Based Metal-Organic Framework as a Drug Carrier.

ABSTRACT: To date, the number of reported mesoporous metal-organic frameworks (MOFs) remains limited. Herein, we report a novel mesoporous potassium-based MOF (K-MOF), designated as KMOF-1, whose precise structure was determined by using single-crystal X-ray diffraction. KMOF-1 used 18-crown-6 units as the organic linkers and potassium ions as the metal centers, forming a framework topological structure with interconnected four-membered rings. The specific surface area of the synthesized KMOF-1 was determined by the Brunauer-Emmett-Teller method, which showed a high specific surface area of 1034 m²/g. KMOF-1 was demonstrated to be a promising drug carrier, exhibiting encapsulation capabilities for various drugs and maintaining stability for a defined period und

SUBMITTER: Fang B 

PROVIDER: S-EPMC12464762 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature