Temperature Abetted Synthesis of Zeolitic Imidazolate Framework-Derived 3D Zn@N-C with MXene and Gold Nanostars-Based Immunosensor for the Detection of Prostate-Specific Antigen.

ABSTRACT: Prostate cancer (PC) is a malignant tumor that develops in the prostate cells of males and is the second most common cancer in men. Therefore, an early and accurate diagnosis of PC is crucial. Current diagnostic approaches are insufficient, highlighting an urgent need for alternative analytical platforms that target specific PC biomarkers in body fluids. With this instigation, we designed an environmentally friendly, disposable, and label-free electrochemical immunosensor based on gold nanostars decorated on ZIF-8-derived zinc with nitrogen-doped carbon at different temperatures (600-1000 °C) with a titanium carbide (MXene) nanosheet (AuNSs/Zn@N-C/MXene) composite modified with a screen-printed carbon electrode (SPCE) to detect prostate-specific antigen (PSA). Zn@N-C-800 °C with MXene poss

SUBMITTER: Sakthivel R 

PROVIDER: S-EPMC12464913 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature