Biomarkers predicting adverse pregnancy outcomes in women living with obesity: a systematic review and meta-analysis.

ABSTRACT:

Objective

To systematically review the literature on associations between antenatal biomarkers and adverse pregnancy outcomes in women with BMI ≥30 kg/m². Data sources: Systematic literature searches used predefined search terms in PubMed, Ovid Embase, Ovid MEDLINE, Scopus, and the Cochrane Central Register of Controlled Trials. Databases were searched from inception to August 2024.

Study eligibility criteria

Interventional and observational studies comparing pregnancy outcomes amongst women with a pre- or early-pregnancy (<20 weeks' gestation) BMI ≥30 kg/m² according to presence or amount of any antenatally measured biomarker were included.

Study appraisal and synthesis methods

Two reviewers independently assessed studies for inclusion against predefined inclu

SUBMITTER: Wishlade T 

PROVIDER: S-EPMC12465041 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature