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Aortic valve replacement in patients with significant aortic regurgitation: Comparing bicuspid and tricuspid aortic valve outcomes.


ABSTRACT:

Background

The role of bicuspid aortic valve (BAV) morphology in left ventricular (LV) remodelling and outcomes in aortic regurgitation (AR) patients undergoing surgical aortic valve replacement (SAVR) remains unclear. This study compares LV function and postoperative outcomes in patients with moderate-to-severe AR, stratified by BAV versus tricuspid aortic valve (TAV) morphology.

Methods

We retrospectively analyzed 323 patients with isolated moderate-to-severe AR undergoing SAVR (BAV: n = 70; TAV: n = 253). Baseline clinical, echocardiographic, surgical, and follow-up data were evaluated. Adverse events were defined as a composite of all-cause mortality and heart failure rehospitalization.

Results

Patients with BAV were a decade younger, were less sympt

SUBMITTER: Zhu CY 

PROVIDER: S-EPMC12465045 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature