OncoProExp: An interactive shiny web application for comprehensive cancer proteomics and phosphoproteomics analysis.

ABSTRACT: Cancer research has been revolutionized by mass spectrometry (MS)-based proteomics, enabling large-scale profiling of proteins and post-translational modifications (PTMs) to identify critical alterations in cancer signaling pathways. However, the lack of comprehensive, user-friendly platforms for integrative analysis limits efficient data exploration, biomarker discovery, and translational insights. To address this, we developed OncoProExp, a Shiny-based interactive web application for in-depth cancer proteomic and phosphoproteomic analyses. OncoProExp offers robust workflows for data preprocessing, interactive visualizations (PCA, hierarchical clustering, heatmaps, gene set enrichment analysis (GSEA)), and functional annotation of gene expression data. Differential expression analysis fac

SUBMITTER: Rahmani ES 

PROVIDER: S-EPMC12465049 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature