Lactate-to-albumin ratio as an independent predictor of mortality in critically ill patients with gastrointestinal bleeding: a retrospective cohort study.

ABSTRACT:

Background

The lactate-to-albumin ratio (LAR) is an established prognostic marker in various critical illnesses; However, its association with gastrointestinal bleeding (GIB) in patients has not been thoroughly investigated. This study evaluates the prognostic role of LAR in critically ill patients with GIB.

Methods

Data were extracted from the publicly available MIMIC-IV database (v3.1). We assessed the prognostic value of the LAR for both short- and long-term mortality using multivariable Cox proportional hazards regression. Survival differences were analyzed using Kaplan-Meier (K-M) curves with log-rank tests. Discrimination ability was evaluated using receiver operating characteristic (ROC) curve analysis, while nonlinear associations were examined using restricted cubic

SUBMITTER: Yang X 

PROVIDER: S-EPMC12465259 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature